| AFB | Air Force Base |
| AFOSH | Air Force Occupational Safety and Health |
| AHJ | Authority Having Jurisdiction |
| ANSI | American National Standards Institute |
| ASAP | Aerospace Safety Advisory Panel |
| CFR | Code of Federal Regulations |
| CMOR |
Canadian Meteor Orbit Radar |
| CO | Contracting Officer |
| CoF | Construction of Facilities |
| COTR | Contracting Officers Technical Representative |
| DASHO | Designated Agency Safety and Health Official |
| DoD | Department of Defense |
| DOE | Department of Energy |
| DOT | Department of Transportation |
| EAV | Experimental Aeronautical Vehicle |
| ELV | Expendable Launch Vehicle |
| EPA | Environmental Protection Agency |
| ESO | Explosive Safety Officer |
| FAA | Federal Aviation Administration |
| FAR | Federal Acquisition Regulation |
| FED-STD | Federal Standard |
| FMEA | Failure Modes and Effects Analysis |
| GAO | General Accountability Office |
| GSE | Government Supplied Equipment |
| HOP | Hazardous Operating Procedure or Hazardous Operating Permit |
| IAEA | International Atomic Energy Agency |
| IAOP | Inter-Center Aircraft Operations Panel |
| INSRP | Interagency Nuclear Safety Review Panel |
| IV&V | Independent Verification and Validation |
| JPL | Jet Propulsion Laboratory, a Federally Funded Research Development Center |
| KHB | Kennedy Handbook |
| LED | Light Emitting Diode |
| LLIS | Lessons Learned Information System |
| MSDS | Material Safety Data Sheet |
| NAICS | North American Industrial Classification System |
| NASA | National Aeronautics and Space Administration |
| NASA SP |
NASA Special Publication |
| NASA-STD | NASA Standard |
| NASA TM |
NASA Technical Memorandum |
| NEPA | National Environmental Policy Act |
| NFPA | National Fire Protection Association |
| NFS | NASA FAR Supplement |
| NFSAM | Nuclear Flight Safety Assurance Manager |
| NIOSH | National Institute of Occupational Safety and Health |
| NPD | NASA Policy Directive |
| NPR | NASA Procedural Requirements |
| NSRS | NASA Safety Reporting System |
| NSS | NASA Safety Standard |
| NSTC | NASA Safety Training Center |
| NSTS | National Space Transportation System |
| OCE | Office of the Chief Engineer |
| OCHMO | Office of the Chief Health and Medical Officer |
| OD |
Orbital Debris |
| OPR | Office of Primary Responsibility |
| OSHA | Occupational Safety and Health Administration |
| OSMA | Office of Safety and Mission Assurance |
| OSTP | Office of Science and Technology Policy |
| PD/NSC | Presidential Directive/National Security Council |
| PHA | Preliminary Hazard Analysis |
| PL | Public Law |
| PM | Performance Measure |
| PMC | Program Management Council |
| PPE | Personal Protective Equipment |
| PRA | Probabilistic Risk Assessment |
| PRP | Personnel Reliability Program |
| PSAR | Preliminary Safety Analysis Report |
| QASAR | Quality and Safety Achievement Recognition |
| RAC | Risk Assessment Code |
| RADCC | Radiological Control Center |
| RCC | Range Commanders Council |
| SAR | Safety Assessment Report, Safety Analysis Report |
| SAS | Safety Analysis Summary |
| SER | Safety Evaluation Report |
| SEMP | Systems Engineering Management Plan |
| SMA | Safety and Mission Assurance |
| SSP | Space Shuttle Program |
| SSTP | System Safety Technical Plan |
| USAR | Updated Safety Analysis Report |
| VPP | Voluntary Protection Program |
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