| AoA | Analysis of Alternatives |
| CCB | Configuration Control Board |
| CDR | Critical Design Review |
| CIO | Chief Information Officer |
| CoF | Construction of Facilities |
| COOP | Continuity of Operations Planning |
| DR | Decommissioning Review |
| DME | Development, Modification, or Enhancement |
| EA | Enterprise Architecture |
| EAPR | Enterprise Architecture Project Review |
| EAC | Estimate at Completion |
| EASR | Enterprise Architecture Service Review |
| ECR | Environmental Compliance and Restoration |
| EVM | Earned Value Management |
| EVMS | Earned Value Management System |
| FAD | Formulation Authorization Document |
| FMR | Financial Management Requirements |
| FAR | Federal Acquisition Regulation |
| GFY | Government Fiscal Year |
| IA | Independent Assessment |
| IBR | Integrated Baseline Review |
| IRM | Information Resource Management |
| IT | Information Technology |
| ITMB | Information Technology Management Board |
| IVR | Independent Validation for Reasonableness |
| KDP | Key Decision Point |
| LCC | Life-Cycle Cost |
| MDAA | Mission Directorate Associate Administrator |
| MdM | Metadata Manager |
| MOA | Memorandum of Agreement |
| MOU | Memorandum of Understanding |
| NAR | Non-Advocate Review |
| NFS | NASA Federal Acquisition Regulation (FAR) Supplement |
| NOA | New Obligational Authority |
| NPD | NASA Policy Directive |
| NPR | NASA Procedural Requirements |
| OCE | Office of Chief Engineer |
| OMC | Operations Management Council |
| OMSI | Other Mission Support Investments |
| O&M | Operations and Maintenance |
| ORR | Operational Readiness Review |
| PAR | Program Approval Review |
| PCA | Program Commitment Agreement |
| PCDR | Program Concept and Definition Review |
| PCR | Project Completion Review |
| PDR | Preliminary Design Review |
| PIR | Program Implementation Review |
| PMB | Program Management Board |
| PMC | Program Management Committee |
| PPBE | Planning, Programming, Budgeting, and Execution |
| RFA | Request for Action |
| RFP | Request for Proposal |
| SCR | System Concept Review |
| SMC | Strategic Management Council |
| SIB | Strategy and Investment Board |
| SRR | System Requirements Review |
| TRR | Test Readiness Review |
| V&V | Verification and Validation |
| WBS | Work-Breakdown Structure |
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