| A&PP | Airframe and Power Plant |
| ACA | Airspace Coordination Areas |
| AD | Aircraft Division |
| AD | Airworthiness Directives |
| AFSRB | Airworthiness and Flight Safety Review Board |
| AGL | Above Ground Level |
| AME | Aviation Medical Examiner |
| AO | Area of Operations |
| ARB | Airworthiness Review Board |
| ARP | Airworthiness Review Process |
| ASM | Aviation Safety Manager |
| ASO | Aviation Safety Officer |
| ATC | Air Traffic Control |
| ATP | Airline Transport Pilot |
| BASH | (U.S. Air Force) Bird/Wildlife Aircraft Strike Hazard |
| BCA | Business Case Analysis |
| BLOS | Beyond Line of Sight |
| CAD | Cartridge-Activated Device |
| CALSTD | Calibration Standard |
| CAS | Commercial Aviation Services |
| CCP | Configuration Control Process |
| CFIT | Controlled Flight into Terrain |
| CFO | Chief Financial Officer |
| CFR | Crash Fire Rescue |
| CONUS | Continental United States |
| COTR | Contracting Officer Technical Representative |
| COTS | Commercial Off-the-Shelf |
| CVR | Cockpit Voice Recorder |
| DA | Decision Altitude |
| DoD | Department of Defense |
| DoT | Department of Transportation |
| EGPWS | Enhanced Ground Proximity Warning System |
| EMI | Electromagnetic Interference |
| EOP | Executive Office of the President |
| ESD | Electrostatic Discharge |
| ETA | Estimated Time of Arrival |
| FAA | Federal Aviation Administration |
| FAIRS | Federal Aviation Interactive Reporting System |
| FAR | Federal Aviation Regulations |
| FBI | Federal Bureau of Investigation |
| FCF | Functional Check Flight |
| FCG | Foreign Clearance Guide |
| FDR | Flight Data Recorder |
| FECA | Federal Employees’ Compensation Act |
| FMR | Financial Management Requirements |
| FOD | Foreign Object Damage |
| FRR | Flight Readiness Review |
| FSCAP | Flight Safety Critical Aircraft Parts |
| FTR | Federal Travel Regulation |
| FTS | Flight Termination System |
| GCO | Ground Control Operator |
| GCS | Ground Control Station |
| GIDEP | Government-Industry Data Exchange Program |
| GPS | Global Positioning System | |
| GSA | General Services Administration |
| GSE | Ground Support Equipment |
| HQ | Headquarters |
| HN | Host Nation |
| IAOP | Inter-Center Aircraft Operations Panel |
| IAW | In Accordance With |
| ICAO | International Civil Aviation Organization |
| ICAP | Inter-Agency Committee on Aircraft Policy |
| IG | Inspector General |
| ILS | Instrument Landing System |
| IMC | Instrument Meteorological Conditions |
| IP | Instructor Pilot |
| IRIS | Incident Reporting Information System |
| JPL | Jet Propulsion Laboratory |
| KSC | John F. Kennedy Space Center |
| LOFT | Line Oriented Flight Training |
| LOS | Line of Sight |
| LRU | Line Replaceable Unit |
| MDA | Minimum Descent Altitude |
| MEL | Minimum Equipment List |
| METCAL | Metrology and Calibration |
| MNPS | Minimum Navigation Perfomance Specifications |
| MOA | Memorandum of Agreement |
| MOU | Memorandum of Understanding |
| MRR | Mission Readiness Review |
| MSL | Mean Sea Level |
| NAARS | NASA Aircraft Anomaly Reporting System |
| NALCOMIS | Naval Aviation Logistics Command Management Information System |
| NAMIS | NASA Aircraft Management Information System |
| NAS | National Airspace |
| NASA | National Aeronautics and Space Administration |
| NAVAIDS | Navigational Aids |
| NESC | NASA Engineering Safety Center |
| NEMS | NASA Equipment Management System |
| NFPA | National Fire Protection Association |
| NOTAM | Notices to Airmen |
| NPD | NASA Policy Directive |
| NODIS | NASA Online Directives Information System |
| NPR | NASA Procedural Requirements |
| NTSB | National Transportation Safety Board |
| OEM | Original Equipment Manufacturer |
| OPM | Office of Personnel Management |
| OSHA | Occupation Safety and Health Administration |
| OMB | Office of Management and Budget |
| ORR | Operations Readiness Review |
| OSMA | Office of Safety and Mission Assurance |
| OTI | One-Time Inspections |
| PAD | Propellant Actuated Device |
| PCI | Pavement Condition Index |
| PCS | Portable Control Station |
| PDM | Programmed Depot Maintenance |
| PIC | Pilot in Command |
| PIP | Product Improvement Publications |
| PPB | Power Plant Bulletin |
| PPC | Power Plant Change |
| PS | Program Support |
| QAI | Quality Assurance Inspector |
| R&D | Research and Development |
| RA | Resolution Advisories |
| RAC | Risk Assessment Code |
| RC | Radio Control |
| RNAV | Random Area Navigation |
| RNP | Required Navigation Performance |
| ROA | Restricted Operations Areas |
| ROA | Remotely Operated Aircraft |
| ROZ | Restricted Operations Zones |
| RPV | Remotely Piloted Vehicle |
| RVR | Runway Visual Range |
| RVSM | Reduced Vertical Separation Minimum |
| SB | Service Bulletin |
| SDLM | Scheduled Depot Level Maintenance |
| SEMO | Supply and Equipment Management Officer |
| SES | Senior Executive Service |
| SI | Service Instruction |
| SIC | Second in Command |
| SM | Statute Mile |
| SODA | Statements of Demonstrated Ability |
| SOP | Standard Operating Procedure |
| STC | Supplemental Type Certificate |
| sUAS | Small Unmanned Aircraft System |
| SUA | Special Use Airspace |
| SUP | Suspected Unapproved Parts |
| TAWS | Terrain Awareness and Warning System |
| TCAS | Traffic Alert and Collision Avoidance System |
| TCP | Tool Control Program |
| TCTO | Time Compliant Technical Order |
| TD | Technical Directive |
| TDY | Temporary Duty |
| TO | Technical Order |
| TOGW | Takeoff Gross Weight |
| UAS | Unmanned Aircraft System |
| VMC | Visual Meteorological Conditions |
| W&B | Weight and Balance |
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