| Directive ID | Subject | Effective Period |
| NASA Continuity of Operations (COOP) Planning Procedural Requirements (Revalidated with Change 3, 9/13/2012) | July 3, 2003 to September 13, 2017 | |
| Requirements for the Conduct of NASA Research and Technology (R&T) | May 30, 2008 to July 30, 2013 | |
| Procedures for Use of Monetary Gifts and Donations by NASA (Revalidated with Change 1, 1/7/2010) | February 23, 2005 to January 7, 2015 | |
| Requests For Waivers Of The Residence Abroad Requirements For Exchange Visitors Sponsored By NASA Contractors And Grantees w/Change 2 (Revalidated January 23, 2008) | November 26, 1997 to November 26, 2013 | |
| NASA Privacy Procedural | August 10, 2007 to June 28, 2013 | |
| Public Appearances of NASA Astronauts w/Change 3 (Revalidated 01/20/11) | January 7, 2000 to January 20, 2016 | |
| NASA Exhibits Program w/Change 2 (Revalidated 03/17/10) | January 9, 1999 to March 17, 2015 | |
| NASA Directives and Charters Procedural Requirements | July 15, 2011 to July 15, 2016 | |
| NASA Records Retention Schedules (w/Change 5, 6/26/09) | February 24, 2003 to August 24, 2014 | |
| NASA Correspondence Management and Communications Standards and Style w/Change 2 (1/21/2011) | March 24, 2006 to March 24, 2016 | |
| Handling Congressional Correspondence And Information Concerning Congressional Activities (Revalidated 07/20/07) | October 31, 2001 to May 31, 2013 | |
| NASA Security Program Procedural Requirements w/Change 2 (4/01/2009) | November 3, 2004 to November 3, 2014 | |
| NASA Classified National Security Information (CNSI) w/Change 1 (11/01/2012) | October 11, 2011 to October 11, 2016 | |
| Personnel Security (Change 2, April 29, 2013) | May 31, 2012 to May 31, 2017 | |
| Identity and Credential Management | August 1, 2012 to August 1, 2017 | |
| Facility Security Assessments | October 4, 2012 to October 4, 2017 | |
| Physical Security Requirements for NASA Facilities and Property | October 4, 2012 to October 4, 2017 | |
| NASA Counterintelligence and Counterterrorism | October 11, 2011 to October 11, 2016 | |
| NASA Occupational Health Program Procedures w/Change 2 (05/17/2013) | October 6, 2009 to October 6, 2014 | |
| Quality Assurance of the NASA Medical Care | May 11, 2010 to May 11, 2015 | |
| Ethics Program Management | April 23, 2007 to August 23, 2013 | |
| Nondiscrimination in Federally Assisted and Conducted Programs | May 11, 2010 to May 11, 2015 | |
| Distribution of Royalties Received by NASA from the Licensing or Assignment of Inventions (REVALIDATED 8/12/08) | August 7, 2003 to August 12, 2013 | |
| NASA Export Control Program | December 27, 2011 to December 27, 2016 | |
| Requirements for Documentation, Approval, and Dissemination of NASA Scientific and Technical Information | April 19, 2011 to April 19, 2016 | |
| Release of NASA Software | August 11, 2010 to August 11, 2015 | |
| NASA Radio Frequency (RF) Spectrum Management Manual | December 5, 2008 to December 5, 2013 | |
| Managing Information Technology | March 20, 2009 to March 20, 2014 | |
| Electronic and Information Technology Accessibility | January 6, 2011 to January 6, 2016 | |
| Security of Information Technology (Revalidated with Change 1, dated May 19, 2011) | May 16, 2006 to May 16, 2016 | |
| NASA Enterprise Architecture Procedures | February 9, 2006 to June 9, 2013 | |
| Identity, Credential, and Access Management | January 6, 2011 to January 6, 2016 | |
| Management of the Senior Executive Service (SES) | March 9, 2007 to March 9, 2014 | |
| Appointment of Personnel To/From NASA | May 8, 2009 to May 8, 2014 | |
| Senior Executive Service Career Appointee Merit Staffing in NASA | March 13, 2007 to March 13, 2014 | |
| Management of Senior Scientific and Technical (ST) and other Senior Level (SL) Positions | April 23, 2007 to April 23, 2014 | |
| NASA Career Transition Assistance Plan, (Revalidated with Change 1, 02/13/2013) | June 6, 2006 to June 6, 2018 | |
| Internal Placement of NASA Employees | December 1, 2010 to December 1, 2015 | |
| NASA Employee Performance Communication System (EPCS) - Change 6 (10/29/10) | May 1, 2007 to May 1, 2014 | |
| Performance Based Reduction In Grade or Removal Actions (Revalidated with Change 1 03/02/2006) | May 7, 1999 to May 7, 2014 | |
| NASA Performance Management System for the Senior Executive Service | March 5, 2008 to March 5, 2014 | |
| NASA Awards and Recognition Program | June 4, 2009 to June 4, 2014 | |
| Position Management and Classification | September 29, 2006 to March 29, 2014 | |
| NASA Pay and Compensation Policy | January 12, 2009 to January 12, 2014 | |
| Attendance and Leave | April 24, 2006 to April 24, 2014 | |
| NASA Telework Program | January 6, 2010 to January 6, 2015 | |
| Federal Employee Labor Management Relations Program | July 2, 2012 to July 2, 2017 | |
| Reasonable Accommodations Procedures | March 28, 2008 to June 28, 2013 | |
| Alternative Dispute Resolution for Discrimination Complaints | May 8, 2009 to May 8, 2014 | |
| Anti-Harassment Procedures | October 6, 2009 to October 6, 2014 | |
| Procedures for Discrimination Complaints Based on Sexual Orientation | June 1, 2012 to June 1, 2017 | |
| NASA Suitability Program | June 4, 2012 to June 4, 2017 | |
| Disciplinary and Adverse Actions (Revalidated w/Change 1 05/05/2006) | May 7, 1999 to May 7, 2014 | |
| Grievance System (Revalidated w/Change 1 05/05/2006) | May 7, 1999 to May 7, 2014 | |
| Plan for a Drug-Free Workplace (REVALIDATED w/Change 1 12/06/06) | July 29, 2006 to July 29, 2014 | |
| Employee Benefits | November 9, 2010 to November 9, 2015 | |
| NPR 4000.1 | NASA Logistics Management Operations Compensating Controls Reviews | April 9, 2010 to April 9, 2015 |
| NASA Materials Inventory Management Manual (Revalidated 2/9/06) | July 29, 1999 to July 29, 2013 | |
| NASA Equipment Management Procedural Requirements | March 30, 2010 to March 30, 2015 | |
| Equipment Management Manual for Property Custodians w/Change 1, 9/11/03 | September 11, 1998 to July 11, 2013 | |
| NASA Personal Property Disposal Procedural Requirements (Revalidated 2/17/06 with Change 1) | July 19, 1999 to June 26, 2013 | |
| Identification and Disposition of NASA Artifacts (Revalidated w/Change 2 1/31/06) | March 16, 1999 to September 16, 2013 | |
| Federal Acquisition Regulation Supplement (NASA/FAR Supplement) [48 CFR 1800-1899] (REVALIDATED 9/16/2008) | August 31, 1997 to December 31, 2013 | |
| Procurement Advocacy Programs w/Change 3, Revalidated 12/09/10 | May 19, 2000 to December 19, 2015 | |
| Industrial Labor Relations Manual (Revalidated April 10, 2013, with admin. changes) | June 23, 1997 to June 30, 2018 | |
| Grant And Cooperative Agreement Handbook (14 CFR 1260) (Revalidated 3/10/2011) | October 19, 2000 to October 19, 2016 | |
| Standard Format for NASA Research Announcements (NRAs) and other Announcements for Grants and Cooperative Agreements (Updated w/Change 2, July 16, 2012) | October 18, 2004 to October 18, 2016 | |
| NASA Spare Parts Acquisition w/Change 2 (12/19/08) | October 28, 2003 to December 31, 2013 | |
| Requirements for Packaging, Handling, and Transportation for Aeronautical and Space Systems, Equipment, and Associated Components | November 10, 2010 to November 10, 2015 | |
| NASA Transportation and General Traffic Management | October 8, 2008 to October 8, 2013 | |
| Protection of Human Research Subjects (Revalidated 7/7/08) | March 28, 2003 to September 7, 2013 | |
| Technical Standards for NASA Programs and Projects | April 22, 2011 to April 22, 2016 | |
| NASA Health and Medical Technical Authority (HMTA) Implementation | November 1, 2011 to November 1, 2016 | |
| NASA Space Flight Program and Project Management Requirements w/Changes 1-10 | August 14, 2012 to August 14, 2017 | |
| Lessons Learned Process (Revalidated w/change 1, 01/22/10 | March 22, 2005 to March 22, 2015 | |
| NASA Information Technology and Institutional Infrastructure Program and Project Management Requirements | November 3, 2008 to November 3, 2013 | |
| NASA Research and Technology Program and Project Management Requirements (w/change 3 dated 04/18/13) | February 5, 2008 to February 5, 2018 | |
| NASA Product Data and Life-Cycle Management (PDLM) for Flight Programs and Projects | March 11, 2011 to March 11, 2016 | |
| NASA Systems Engineering Processes and Requirements | April 18, 2013 to April 18, 2018 | |
| NASA Software Engineering Requirements | November 19, 2009 to November 19, 2014 | |
| NASA Technology Commercialization Process w/ Change 1 (4/9/04) | December 20, 2001 to December 20, 2013 | |
| Aircraft Operations Management Manual | July 15, 2011 to July 15, 2016 | |
| Agency Risk Management Procedural Requirements | December 16, 2008 to December 16, 2013 | |
| Planetary Protection Provisions for Robotic Extraterrestrial Missions | April 20, 2011 to April 20, 2016 | |
| NASA Cultural Resources Management | June 20, 2012 to June 20, 2017 | |
| Affirmative Procurement Program and Plan for Environmentally Preferable Products (REVALIDATED 4/3/09 w/change 3) | June 4, 2004 to June 4, 2014 | |
| NASA Environmental Management System | September 22, 2009 to September 22, 2014 | |
| Energy Efficiency and Water Conservation w/Change 2 (4/04/08) REVALIDATED | March 15, 2001 to June 15, 2013 | |
| NASA National Environmental Policy Act Management Requirements | August 1, 2012 to August 1, 2017 | |
| Environmental Compliance and Restoration Program | July 18, 2011 to July 18, 2016 | |
| NASA Procedural Requirements for Mishap and Close Call Reporting, Investigating, and Recordkeeping w/Change 6 (10/24/2011) | May 23, 2006 to October 24, 2016 | |
| Human-Rating Requirements for Space Systems (w/change 4 dated 8/21/2012) | May 6, 2008 to May 6, 2016 | |
| Risk Classification for NASA Payloads (Revalidated July 9, 2008) | June 14, 2004 to July 9, 2013 | |
| Technical Probabilistic Risk Assessment (PRA) Procedures for Safety and Mission Success for NASA Programs and Projects | June 7, 2010 to June 7, 2015 | |
| Safety and Mission Assurance (SMA) Audits, Reviews, and Assessments | May 24, 2011 to May 24, 2016 | |
| NASA Occupational Safety and Health Programs | March 5, 2012 to March 5, 2017 | |
| NASA Emergency Preparedness Procedural Requirements | January 9, 2009 to January 9, 2014 | |
| NASA General Safety Program Requirements (w/Change 9 dated 2/08/13) | March 12, 2008 to March 12, 2014 | |
| Range Flight Safety Program (updated with Change 2) | September 17, 2010 to September 17, 2015 | |
| NASA Procedural Requirements for Limiting Orbital Debris (w/ Change 1 - 5/14/09) | May 14, 2009 to May 14, 2014 | |
| Expendable Launch Vehicle Payload Safety Program | May 30, 2008 to November 30, 2013 | |
| Procedures for Exchanging Parts, Materials, Software, and Safety Problem Data Utilizing the Government-Industry Data Exchange Program (GIDEP) and NASA Advisories | February 13, 2013 to February 13, 2018 | |
| Management of Government Quality Assurance Functions for NASA Contracts (w/change 1, dated 8/9/2010) | August 2, 2006 to August 31, 2013 | |
| Real Estate Management Program | June 21, 2010 to June 21, 2015 | |
| Center Master Planning | February 13, 2013 to February 13, 2018 | |
| Facility Project Requirements | January 28, 2008 to November 28, 2013 | |
| Facilities Maintenance and Operations Management | November 18, 2008 to November 18, 2013 | |
| NASA Health and Medical Requirements for Human Space Exploration | July 17, 2012 to July 17, 2017 | |
| Care and Use of Animals | December 2, 2011 to December 2, 2016 | |
| Financial Management Requirements Overview (Revalidated w/change 1 - 7/10/12) | September 30, 2008 to September 30, 2017 | |
| The Continuous Monitoring Program and Financial Management Operating Procedures | August 9, 2012 to August 9, 2017 | |
| Financial Management Internal Control | September 30, 2008 to January 30, 2015 | |
| Official Representational Fund w/Changes 1 - 5 (Revalidated 05/10/2012) | November 4, 2002 to November 4, 2017 | |
| Advances and Prepayments | July 26, 2011 to July 26, 2016 | |
| The Antideficiency Act (Revalidated May 21, 2013 w/change 1) | September 30, 2008 to September 30, 2018 | |
| Cash Management and Improper Payments | September 30, 2008 to November 30, 2014 | |
| Cost Accruals | September 30, 2008 to May 30, 2015 | |
| Reimbursable Agreements | February 25, 2013 to February 25, 2018 | |
| Working Capital Fund Policies and Requirements | September 30, 2008 to September 30, 2014 | |
| NASA Financial Information Systems | September 30, 2008 to November 30, 2014 | |
| Accounting General Overview (Revalidated 3/27/13 with Change 1) | September 30, 2008 to September 30, 2018 | |
| Cash and Fund Balance with Treasury | September 30, 2008 to September 30, 2014 | |
| Journal Voucher Preparation and Approval and Intragovernmental Transactions | August 16, 2011 to August 16, 2016 | |
| Property, Plant, and Equipment and Operating Materials and Supplies | January 6, 2011 to January 6, 2016 | |
| Revenue, Unfunded Liabilities and Other Liabilities | September 30, 2008 to September 30, 2013 | |
| Special Accounts | April 11, 2011 to April 11, 2016 | |
| Financial Management Reports - Accounting | March 15, 2013 to March 15, 2018 | |
| External Reports - Budget | September 30, 2008 to March 30, 2015 | |
| Budget Formulation | December 24, 2008 to March 24, 2015 | |
| Budget Execution | December 24, 2008 to May 24, 2015 | |
| NASA Contractor Financial Management Reporting | May 27, 2011 to May 27, 2016 | |
| Accounts Receivable | September 30, 2008 to September 30, 2014 | |
| Accounts Payable | September 30, 2008 to January 30, 2015 | |
| Payroll | September 30, 2008 to January 30, 2015 | |
| Disbursements | September 30, 2008 to March 30, 2015 | |
| Billings and Collections | September 30, 2008 to November 30, 2014 | |
| Financial Management of Contractor Claims Against NASA | January 18, 2013 to January 18, 2018 | |
| Claims for Erroneous Payment of Pay and Allowances, Travel and Transportation, Relocation Expenses and Allowances | September 30, 2008 to September 30, 2013 | |
| Vital Records and Emergency Operations | September 30, 2008 to September 30, 2013 | |
| NASA's Management of Grants and Cooperative Agreements | November 10, 2011 to November 10, 2016 | |
| Investments (Revalidated, November 10, 2011) | September 30, 2008 to September 30, 2016 | |
| Travel (w/change 3) dated September 12, 2011 | September 30, 2008 to May 30, 2015 |